Enables direct, single-ion detection for high-sensitivity and confident analysis of complex analytes.

The Direct Mass Technology mode option for Tribrid MS delivers advanced performance, versatility, and streamlined usability, enabling rapid and confident characterisation of complex biological systems. Designed for demanding analytical workflows, it enhances sensitivity, throughput, and data quality across proteomics to pharmaceutical applications.

Key Features

Single-ion detection for direct charge assignment, eliminating reliance on isotope or charge state patterns
Alternative fragmentation options for detailed characterisation of proteins, oligonucleotides, and small molecules
Flexible multi-stage (MSn) workflows and ion parallelisation maximise data collection speed and quality
Dedicated options for MultiOmics, Structural Biology, BioPharma, and Small Molecule applications
Advanced fragmentation, real-time library search, and auto-calibration features
Dual ion-routing multipoles improve scan rate and sensitivity
Environmentally friendly, oil-free dry pump reduces maintenance requirements
Pre-built method templates for diverse applications

*Some features, such as the Native MS, PTCR, Direct Mass Technology, and Easy-ETD options, are only available in select editions (MultiOmics, Structural Biology, BioPharma).

Specifications

Compatibility	Orbitrap Tribrid Apex MS, Orbitrap Ascend Tribrid MS
Model	Direct Mass Technology mode option for Tribrid MS
*Mass Range (Native MS option)**	Up to m/z 16,000 (MS1) and m/z 20,000 (MS2)
Quadrupole Isolation	Up to m/z 12,000
Unit Size	Each
Additional Features	Real-time library search, Auto-ready 2 ion source, EASY-IC ion source for internal calibration, PTCR and Easy-ETD options for enhanced proteoform and PTM characterisation

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Key Features

Single-ion detection for direct charge assignment, eliminating reliance on isotope or charge state patterns
Alternative fragmentation options for detailed characterisation of proteins, oligonucleotides, and small molecules
Flexible multi-stage (MSn) workflows and ion parallelisation maximise data collection speed and quality
Dedicated options for MultiOmics, Structural Biology, BioPharma, and Small Molecule applications
Advanced fragmentation, real-time library search, and auto-calibration features
Dual ion-routing multipoles improve scan rate and sensitivity
Environmentally friendly, oil-free dry pump reduces maintenance requirements
Pre-built method templates for diverse applications

*Some features, such as the Native MS, PTCR, Direct Mass Technology, and Easy-ETD options, are only available in select editions (MultiOmics, Structural Biology, BioPharma).

Specifications

Compatibility	Orbitrap Tribrid Apex MS, Orbitrap Ascend Tribrid MS
Model	Direct Mass Technology mode option for Tribrid MS
*Mass Range (Native MS option)**	Up to m/z 16,000 (MS1) and m/z 20,000 (MS2)
Quadrupole Isolation	Up to m/z 12,000
Unit Size	Each
Additional Features	Real-time library search, Auto-ready 2 ion source, EASY-IC ion source for internal calibration, PTCR and Easy-ETD options for enhanced proteoform and PTM characterisation